Phentermine is an appetite suppressant of the amphetamine and phenethylamine class.It is approved as an appetite suppressant to help reduce weight in obese patients when used short-term and combined with exercise, diet, and behavioral modification. It is typically prescribed for individuals who are at increased medical risk because of their weight and works by helping to release certain chemicals in the brain that control appetite.

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Orlistat is the first weight loss drug approved by the Food and Drug Administration for sale in the US as an over the counter (OTC) product. GSK Consumer Healthcare will market the OTC orlistat version under the brand name alli™ (pronounced AL-eye). The Alli diet product is a fat blocker the prevents the body from absorbing excess dietary fat.

The Food and Drug Administration (FDA) approved an over the counter version of the fat-blocking weight loss pill orlistat. Before you get excited, there are multiple caveats. In order for the pill to work, you must diet and exercise. The pill has been shown to cause stomach discomfort, loose still and some oily spotting.

The Federal Trade Commission on Thursday fined the marketers of four weight loss pills $25 million for making false advertising claims ranging from rapid weight loss to reducing the risk of cancer.FTC Chairman Deborah Platt Majoras said the products would remain on store shelves, but that the companies would have to stop making the false claims